“Surface morphology and biochemical characteristics of electrospun cellulose nanofibril reinforced PLA/PBS hollow scaffold for tissue engineering”

The treatment of organ failure is one of the primary concerns of healthcare because available organ transplantation techniques have multiple disadvantages. Currently, tissue engineering has emerged as an ingenious approach in which biocompatible and biodegradable scaffolds are used as the alternative to allograft. The PLA/PBS solid electrospun scaffolds have gained a boosted interest in this field. However deficient nutrient diffusion in the implanted area, poor permeability of the seeded cells and insufficient vascularization has been postponing clinical translation of the electrospun scaffolds. In the present research, we have fabricated CNF/PLA/PBS hollow fibrous scaffolds using two different core templates such as mineral oil and glycerol. The physical properties and function were analyzed by using tensile test, scanning electron microscope, contact angle and invitro degradation. The quantity of attached …